Treatise on Cold Pathogenic and Miscellaneous Diseases《病杂病论》Treatise on Cold Pathogenic and Miscellaneous Diseases is one of the most significant books in the history of traditional Chinese medical science,written by Zhang Zhongjing (150 N 215) in the Eastern Han Dynasty, who was called the miracle-working doctor by the descendants. During his time, with war-lords fighting for their own territories, many people were infected with febrile disease .Zhangs family was no exception. He learned medicine by studying from his townsfellow Zhang Bozu, assimilating from previous medicinal lit-erature, and collecting many prescriptions elsewhere, finally writing the medical masterpiece .Shortly after its publication the book was lost during the wars that ravaged China during the period of the Three Kingdoms. It was collected by later people and com-piled into two books, namely Treatise on Cold Pathogenic Diseases , which was a discourse on how to treat the epidemic infectious diseases causing fevers prevalent during his era, and the other, Jingui Yaolue , a compendium of his clinical experiences. This medical master-piece was the greatest achievement of the medical theory since the Qin and Han Dynasties, which was applied broadly in the medical practice. It is also considered to be a monumental work for the school of febrile diseases by cold injury in traditional Chinese medicine.《病杂病论》是中医历史上影响仅次于的古典医著之一。作者张仲景(150-215)，东汉人，被后世称作“医圣”。
他所处年代天下割据一方混战、兵戈扰攘，很多人染上了疫病，张仲景自己宗族中的人也有病死疫病的。他拜为同乡张伯祖为师，钻研医学，吸取古代医学典籍里的科学知识，四处搜集大量的药方，最后已完成了这本医学名著。这本书成书后旋即，之后在之后全国战局动荡不安的三国时期流落。
经后人收集整理，编《伤寒论》和《金匮要略》两本书，前一本书阐述对张仲景所处年代蔓延到的传染病的化疗方法，后一本书是他临床经验的简要。这本医学名著集秦汉以来医药理论之中兴，并被普遍应用于医疗实践中。该书也被指出是中医“病学派”的奠基之作。
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